NEWS: Curebase closes $40M Series B with strategic investment by Gilead. Read about it in TechCrunch, Fierce Biotech, andEndpoints News.

Press release

Curebase, LEVEL Announce Clinical Trial to Determine Whether Cannabinoids Can Help Veterans Sleep Better

SAN FRANCISCO, Nov. 3, 2021 /PRNewswire/ -- Curebase, a company committed to democratizing access to clinical studies, and LEVEL, a science-driven cannabis company on the cutting edge of cannabinoid research and innovation, today announced a decentralized clinical study to determine whether cannabis can have a positive impact on sleep quality for U.S. Veterans. LEVEL is pleased to co-sponsor this study with the Veterans Cannabis Group to identify and recruit participants for this research.

Military Veterans are four times more likely than members of the general public to have obstructive sleep apnea (OSA), according to the National Sleep Foundation. And a recent study showed that 92% of active-duty personnel with post-traumatic stress disorder (PTSD) reported clinically significant levels of insomnia, compared to 28% of those without PTSD.

"Sleep disruptions can affect everyone's health and overall quality of life, but the Veteran population in particular is vulnerable," said Curebase CEO Tom Lemberg. "The Curebase solution was designed for research trials to be able to measure a patients real life experience, in any location, including at home in their own bed. We are also uniquely supporting this population with our staff of virtual research coordinators, that will track participants progress, and proactively reach out with supportive conversations throughout the study. We're excited to partner with LEVEL in this decentralized clinical trial that may lead to genuine relief from sleep disorders for the brave people who have served our country."

The study will involve 109 Veteran volunteers and is scheduled to run for seven to eight weeks, with results to be released early next year. Participants in the decentralized clinical trial will be given measured doses of CBG, one of several rare cannabinoids in cannabis plants. Fitbits will be used to track and report on sleep quality and levels of participants through the Curebase platform, along with other physical and activity metrics.

To help recruit Veterans for the trial, Curebase and LEVEL partnered with several Veterans' advocacy groups, including the Veterans Cannabis Group, Operation EVAC, and the Santa Cruz Veterans Alliance.

"While this is a fully virtual trial, we wanted that front door to be through an organization that Veterans know and trust," said LEVEL founder and CEO Chris Emerson, himself a Veteran of the U.S. Navy. "Combining the work of these terrific Veterans' organizations with Curebase's trial platform and virtual study staff, we're able to focus on connecting Veterans with the clinical aspects and benefits of the study remotely, while feeling closely supported by real people from our Veteran partners and Curebase's research staff."

Curebase's decentralized clinical trial model ensures more diverse studies because unique populations – which typically are underrepresented in clinical trials – can be included. The decentralized platform makes it easy for Veterans to participate, no matter where they are located, in addition to providing them proactive and real-time support through the use of data empowered virtual research coordinators. The Curebase platform and virtual site empowers sponsors, CROs and physicians from practices of all sizes to conduct clinical research, including private practices, independent clinics, and large academic research sites.

LEVEL's mission is to create unique, targeted effects-based cannabis products by formulating cannabinoids in ratios not accessible from the plant alone and at consistent levels of purity and desired effects. The company hopes to destigmatize cannabis use and encourage continued clinical research into its potential benefits.

About LEVEL

LEVEL is a cannabinoid research and development company that is unlocking the true potential of cannabis to deliver brand-new highs with targeted effects. LEVEL formulates with cannabinoids you don't often hear about (CBG, CBN, THCa,THCv, Delta-8 THC) as well as the ones you do (Delta-9 THC and CBD) into swallowable and dissolvable tablets. LEVEL's products are scientifically designed to deliver the desired effect, every time. Whether you're looking to focus on a project, get a good night's sleep, prevent a hangover, relieve stress, or soothe aches and pains, there's a unique cannabinoid profile for that. We crafted the range of doses and intake methods we offer with the intention of providing tools that help you discover what your body responds to best—no matter your experience level with cannabis.

About Curebase

At Curebase, our mission is to bring quality medical innovations to patients faster and improve human wellbeing through more efficient clinical studies. We are proving that clinical research can be radically accelerated if we empower physicians everywhere to enroll patients in the communities where they live. By applying cutting edge clinical software and remote study management techniques to the problem, we are reinventing clinical trials and research from the ground up.

Media Contact:

Shawn Malloy

media@curebase.com

315-882-5310

Curebase, LEVEL Announce Clinical Trial to Determine Whether Cannabinoids Can Help Veterans Sleep Better

SAN FRANCISCO, Nov. 3, 2021 /PRNewswire/ -- Curebase, a company committed to democratizing access to clinical studies, and LEVEL, a science-driven cannabis company on the cutting edge of cannabinoid research and innovation, today announced a decentralized clinical study to determine whether cannabis can have a positive impact on sleep quality for U.S. Veterans. LEVEL is pleased to co-sponsor this study with the Veterans Cannabis Group to identify and recruit participants for this research.

Military Veterans are four times more likely than members of the general public to have obstructive sleep apnea (OSA), according to the National Sleep Foundation. And a recent study showed that 92% of active-duty personnel with post-traumatic stress disorder (PTSD) reported clinically significant levels of insomnia, compared to 28% of those without PTSD.

"Sleep disruptions can affect everyone's health and overall quality of life, but the Veteran population in particular is vulnerable," said Curebase CEO Tom Lemberg. "The Curebase solution was designed for research trials to be able to measure a patients real life experience, in any location, including at home in their own bed. We are also uniquely supporting this population with our staff of virtual research coordinators, that will track participants progress, and proactively reach out with supportive conversations throughout the study. We're excited to partner with LEVEL in this decentralized clinical trial that may lead to genuine relief from sleep disorders for the brave people who have served our country."

The study will involve 109 Veteran volunteers and is scheduled to run for seven to eight weeks, with results to be released early next year. Participants in the decentralized clinical trial will be given measured doses of CBG, one of several rare cannabinoids in cannabis plants. Fitbits will be used to track and report on sleep quality and levels of participants through the Curebase platform, along with other physical and activity metrics.

To help recruit Veterans for the trial, Curebase and LEVEL partnered with several Veterans' advocacy groups, including the Veterans Cannabis Group, Operation EVAC, and the Santa Cruz Veterans Alliance.

"While this is a fully virtual trial, we wanted that front door to be through an organization that Veterans know and trust," said LEVEL founder and CEO Chris Emerson, himself a Veteran of the U.S. Navy. "Combining the work of these terrific Veterans' organizations with Curebase's trial platform and virtual study staff, we're able to focus on connecting Veterans with the clinical aspects and benefits of the study remotely, while feeling closely supported by real people from our Veteran partners and Curebase's research staff."

Curebase's decentralized clinical trial model ensures more diverse studies because unique populations – which typically are underrepresented in clinical trials – can be included. The decentralized platform makes it easy for Veterans to participate, no matter where they are located, in addition to providing them proactive and real-time support through the use of data empowered virtual research coordinators. The Curebase platform and virtual site empowers sponsors, CROs and physicians from practices of all sizes to conduct clinical research, including private practices, independent clinics, and large academic research sites.

LEVEL's mission is to create unique, targeted effects-based cannabis products by formulating cannabinoids in ratios not accessible from the plant alone and at consistent levels of purity and desired effects. The company hopes to destigmatize cannabis use and encourage continued clinical research into its potential benefits.

About LEVEL

LEVEL is a cannabinoid research and development company that is unlocking the true potential of cannabis to deliver brand-new highs with targeted effects. LEVEL formulates with cannabinoids you don't often hear about (CBG, CBN, THCa,THCv, Delta-8 THC) as well as the ones you do (Delta-9 THC and CBD) into swallowable and dissolvable tablets. LEVEL's products are scientifically designed to deliver the desired effect, every time. Whether you're looking to focus on a project, get a good night's sleep, prevent a hangover, relieve stress, or soothe aches and pains, there's a unique cannabinoid profile for that. We crafted the range of doses and intake methods we offer with the intention of providing tools that help you discover what your body responds to best—no matter your experience level with cannabis.

About Curebase

At Curebase, our mission is to bring quality medical innovations to patients faster and improve human wellbeing through more efficient clinical studies. We are proving that clinical research can be radically accelerated if we empower physicians everywhere to enroll patients in the communities where they live. By applying cutting edge clinical software and remote study management techniques to the problem, we are reinventing clinical trials and research from the ground up.

Media Contact:

Shawn Malloy

media@curebase.com

315-882-5310

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Entire article

Curebase Hires Katri Langel as Senior Director of Program Development for Europe

Katri Langel, international IT and clinical research expert, joins Curebase as Senior Director of Program Development for Europe

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Curebase Hires Wayne Bowden as Vice President of Business Development

Curebase names clinical trials veteran, Wayne Bowden, as Vice President of Business Development to lead new growth and expansion efforts

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It's a virtual world: Curebase, AppliedVR team up on virtual reality-based, at-home clinical trials

AppliedVR will test its virtual-reality-based digital therapeutics dtx across five studies using the decentralized clinical trials software from Curebase

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Curebase Secures Jane Myles as Vice President of Clinical Trial Innovation

Curebase has named tenured clinical research expert Jane Myles as vice president of clinical trial innovation

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Curebase, Adaptive Biotechnologies Announce Collaboration to Expand Clinical Study Access

Curebase decentralized clinical trial model will be used to study effectiveness in infections disease study

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Introducing ‘BYOP’ Clinical Trials

Curebase is promoting the concept of 'bring-your-own-physician' clinical trials.

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Curebase Names Paul Donnelly as Senior Vice President of Enterprise Strategy

Industry veteran, Paul Donnelly, brings more than two decades of success building healthcare companies to Curebase

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Startups Cash In as Venture Funding for Digital Health Rises

Curebase featured in Wall Street Journal among startups realizing venture capital boom in digital health

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Curebase, InBios Announce Results of Virtual Clinical Trial of InBios COVID-19 Rapid Detection Test Using Curebase Platform

Curebase decentralized trials platform used to study efficacy of diagnostic test

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Curebase Nabs $15M for Siteless Trials that Revolve 'Around the Patient's Lifestyle'

Curebase has raised a $15 million series A for a new approach to decentralized trials that goes beyond the current drop of virtual trial platforms.

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Cofactor Genomics Begins Multi-Site Clinical Trial for Immunotherapy Prediction Assay

Curebase is participating as a CRO partner with Cofactor Genomics in first multicenter clinical trial of its OncoPrism immunotherapy response prediction assay

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Non-Traditional Clinical Trial Sites Powered by the Curebase System Support Emergency Use Authorization of New Rapid COVID-19 Test

Operationalizing drive-through COVID testing locations as clinical research sites provided a safe and convenient way to enroll and consent potential participants in key diagnostic validation study

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CLM Tests Drug Plus Digital Combo for High Blood Pressure

CLM drug and DTx digital therapeutics study with Curebase

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Preliminary Outcomes of a Digital Therapeutic Intervention for Smoking Cessation in Adult Smokers: Randomized Controlled Trial

Digital interventions delivered through smartphones offer a promising alternative to traditional methods, but little is known about their effectiveness.

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Remote Care Powered CURE-19 Platform Enables At Home COVID-19 Clinical Trials

Curebase launches the CURE-19 Platform to provide a resource for researchers seeking to better understand COVID-19 as the pandemic begins

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